Showing posts with label screen. Show all posts
Showing posts with label screen. Show all posts

Monday, September 13, 2021

Specimen validity testing the test before the (drug) test

Specimen validity testing the test before the (drug) test

Specimen validity testing (SVT) is performed on a urine drug screen specimen to detect substitution, adulteration, or dilution.

Specimen validity testing (SVT) is a critical component of urine drug screening programs. The process of collecting and testing urine samples for drugs of abuse can be susceptible to adulteration or substitution, making it challenging to ensure accurate test results. 

Specimen validity testing (SVT) is using substitution techniques,diluting urine, or adding a substance to a sample.

CharacteristicsNormal Range
Creatinine, mg/dL20–400
Specific gravity1.002–1.030
pH4.5–8.0
Temperature, within 4 minutes of voiding, °F90–100


 SVT is a multifaceted process that includes various methods and techniques.

 Dilution When someone drinks a significant amount of water shortly before providing a urine sample for donation or due to certain physiological conditions, it can lead to diluted urine. This dilution can cause drug or metabolite concentrations to fall below the initial test cutoff, potentially resulting in a false negative outcome. Dilution will mainly effect creatinine and specific gravity. 

 

Creatinine: Creatinine is a natural substance found in urine. It is created when muscle tissue breaks down and is eliminated from the body through the kidneys. Typically, the concentration of creatinine in urine falls within the range of 20 to 400 mg/dL. However, levels outside of this range can indicate factors such as excessive fluid intake, renal failure, diet, or various other medical conditions.

Specific Gravity: Specific gravity (SG) is a measure of the density of a liquid compared to the density of water. It helps determine the concentration of dissolved particles in a urine sample. A decrease in SG values may be attributed to factors like excessive fluid intake,

 

 

 Adulteration —Adding a substance to a specimen after it has been collected. The product added is designed to mask the presence of, or chemically destroy, the drug or drug metabolite that the specimen may contain. An adulterant product may be added with the intention of adversely affecting the testing reagents.

Adulterated Specimen

Urine samples with a pH level below 4.0 or above 9.0 are considered adulterated. An adulterated specimen refers to a urine sample that contains a substance not typically found in urine or an endogenous substance present at an abnormal concentration compared to normal physiological levels. 

Adulterants are products added to the urine with the purpose of masking or chemically destroying the presence of drugs or drug metabolites that the specimen may contain. Adulterant products can also be added to interfere with the testing reagents, or in the case of liquid synthetic urine, act as a preservative to maintain its stability over time.

  Some common oxidants used to attempt to alter urine drug test results are bleach, biocides, nitrate, chromate, iodate, and peroxidase. A positive result for oxidant activity should be considered when interpreting drug results.

 The most popular liquid urine product contains biocides and peroxides and if use din a reputable lab will result in “not consistent with human urine”

pH


The pH level of a urine sample indicates its acidity or alkalinity. Typically, urine pH values range from 4.5 to 9.0. However, if urine specimens are stored under unfavorable conditions such as high temperatures, the pH may rise as high as 9.5. Abnormally high or low pH levels can suggest tampering or adulteration of the sample.

When assessing urine samples, creatinine, specific gravity (SG), and pH are taken into account to determine their validity. All three criteria must fall within the range of normal human urine for a sample to be considered valid. 

 

 These tests are used to assess the validity of the urine specimen by determining its composition and consistency. A urine sample that falls outside the expected ranges for any of these parameters may be indicative of tampering or adulteration.

Urine StatesDescription
DilutedUrine creatinine ≥ 2 mg/dL but < 20 mg/dL
Specific gravity > 1.001 but < 1.030

SubstitutedUrine creatinine < 2 mg/dL
Specific gravity < 1.001 or > 1.020

AdulteratedpH < 3 or > 11
Nitrite concentration > 500 mcg/mL
Chromium concentration > 50 mcg/mL
Presence of: Halogen (bleach, iodine, fluoride), glutaraldehyde, pyridine, surfactant

In addition to these methods, SVT also involves chain of custody procedures, including documentation and tracking of the sample from collection to testing. This ensures that the sample has not been tampered with or substituted during the collection process.

The use of SVT is essential for maintaining the integrity of urine drug screening programs. It provides a reliable mechanism for detecting attempts to alter or adulterate urine specimens and ensures accurate test results. SVT can help prevent false negatives or false positives, which can have significant consequences for individuals undergoing drug testing.

It is important to note that SVT is not foolproof and can be susceptible to manipulation by individuals attempting to cheat the system. However, the use of multiple SVT methods and stringent chain of custody procedures can help minimize the risk of tampering or substitution.

In conclusion, SVT is a critical component of urine drug screening programs. It involves various methods and techniques to assess the validity of urine specimens and detect attempts to tamper with or adulterate them. The use of SVT helps maintain the integrity of drug testing programs and ensures accurate test results.



 Watch a Sample Validly Test  on  Synthetic urine  

 showing proper validity levels of the FAKE IT synthetic urine 



Sunday, October 7, 2018

Home Urine test and what the Faint Line means


Negative or Positive Test Result ?

 


ALL THC LINES ARE FAINT

 IF YOU CAN SEE IT THEN ITS NEGATIVE 


 Is your self test Qualitative or  Semi quantitative  ?

A very common question with people who are worried about seeing a faint line on the home reagent dip strip/cup  test is what does this mean ? 
These are strips which serve different purposes, such as a qualitative strip that only determines if the sample is positive or negative, such as most cheap single store bought dip strip test ( can be cup type as well).  
 
These are a basic preliminary qualitative (quality )  test and thus are not SEMI quantitative  (quantity ) test so they will not show a estimate of a quantitative result in which a color reaction is proportional to the concentration of the substance in sample carried out by comparing the test pad to a chart or react to a lighter / darker line like a CARD or CUP that is SEMI quantitative . 

SEMI quantitative self urine test

Each one of these has a different cut off level and in this case lines get lighter due to lower cut off . A
s you see the lowest is very faint but just as negative as the highest dark line typical of coke and opiate .


LONG STORY SHORT PEOPLE 

AS LONG AS YOU SEE TWO LINES ITS NEGATIVE  NO MATTER HOW FAINT

 

FAINT LINE ON PRELIMINARY QUALITATIVE   DOES NOT MEAN BORDERLINE

 

 If a strip also used in cups has multi colored indicators its a SEMI quantitative  (quantity ) typical of a Validation panel in addition to the drug screen . These will show If the creatinine and specific gravity (urine density),Ph ,nitates are in range ( this shows if sample is diluted) , as well as other factors to determine if sample is in human range and even shows no additive are present.

  



 

 

 

 

 

 

SVT   SPECIMEN VALIDITY TEST

Sometimes a lab will use a reagent stick validation before "accepting" the sample to sent to the lab for drug screening . regardless all samples received at lab will perform validity screen.

 a validation test verifies its ph, color, specific gravity ( verifies dilution ) creatnine level ( not creatine) and looks for nitrates or non urine AGENTS


READING THE STICK   OF SELF TEST


When reading the drug test result, you will find a line at the very top of every testing window and that is the control region (C). The test is not considered valid without this line. Result is considered negative when a colored line appears in both the control (C) and test (T) region. If the colored line appears in the control region but not in the test region, the test is considered to be positive. Nevertheless, presence of any faint line in the test region (T) will indicate negative results no matter how light it is.



Presumptive Positive: One colored line is visible in the control (C) zone for that drug. No colored line whatsoever appears in the test (T) zone, indicating a presumptive positive result for the corresponding drug.
Negative: Colored lines are visible in both the control (C) and test (T) zones, indicating that concentration of the drug is below the detection limit of the test or not present. 

 

 VAST MAJORITY OF SELF TEST ARE CHEAP SINGLE STICK REAGENT  

As long as your not diluted  and not using first morning pee you get best reading . If doing multiple during a detox do them same time of day  no heavy or excessive  fluid intake. If you see a faint line then it will most likely be a little darker with a little extra fluid  but your good just don't super dilute as this will render a DILUTE sample for re test . 

 






 

 

 

Friday, June 1, 2018

Urine Validation. The Test before the Drug Screen

 

 Urine Specimen validity testing (SVT)  The Test Before the Test 

 

Specimen validity testing (SVT) is a critical component of urine drug screening programs. The process of collecting and testing urine samples for drugs of abuse can be susceptible to adulteration or substitution, making it challenging to ensure accurate test results. SVT is a mechanism used to assess the integrity of urine specimens and detect any attempts to tamper with or adulterate them.

SVT is a multifaceted process that includes various methods and techniques. Some of the primary methods used in SVT include testing for pH, creatinine, specific gravity, and temperature. These tests are used to assess the validity of the urine specimen by determining its composition and consistency. A urine sample that falls outside the expected ranges for any of these parameters may be indicative of tampering or adulteration.

Another common SVT method is the use of oxidizing agents, such as bleach or nitrite, which can be added to urine to mask the presence of drugs. These agents can cause a false negative result, indicating that the urine sample is drug-free, even if drugs are present. However, SVT can detect the presence of these oxidizing agents and other adulterants, allowing for accurate test results.

In addition to these methods, SVT also involves chain of custody procedures, including documentation and tracking of the sample from collection to testing. This ensures that the sample has not been tampered with or substituted during the collection process.

The use of SVT is essential for maintaining the integrity of urine drug screening programs. It provides a reliable mechanism for detecting attempts to alter or adulterate urine specimens and ensures accurate test results. SVT can help prevent false negatives or false positives, which can have significant consequences for individuals undergoing drug testing.

It is important to note that SVT is not foolproof and can be susceptible to manipulation by individuals attempting to cheat the system. However, the use of multiple SVT methods and stringent chain of custody procedures can help minimize the risk of tampering or substitution.

In conclusion, SVT is a critical component of urine drug screening programs. It involves various methods and techniques to assess the validity of urine specimens and detect attempts to tamper with or adulterate them. The use of SVT helps maintain the integrity of drug testing programs and ensures accurate test results.

 

Most times a collection center / lab will use a reagent stick validation before "accepting" the sample to be sent to the lab for drug screening.  A quantitative validation test verifies its ph, color, specific gravity ( verifies dilution ) creatinine level and looks for nitrates or non urine AGENTS.  This dentures wasting time testing bad synthetic or adulterated urine.

This video will show the validation screen perimeters while showing the levels of out FAKE IT Synthetic Urine by PASSITKIT.COM 

 

Fake It  Synthetic urine Validation Screening



Fake It synthetic urine test normal in all categories

FAKE IT  Is sold at Hair Razor Detox