Creatine used in Dilution for drug testing how its being done wrong.

Creatine used in Dilution  for drug testing how its being used wrong.  

 Dilution is ...

Dilution refers to the process of decreasing the concentration of a urine sample by consuming excessive fluids with the intention of manipulating a negative outcome on a drug test. Another approach is consuming substances like diuretics (e.g., coffee, cranberry juice) that increase urine output.However, it's important to note that urine drug tests have measures in place to detect dilution attempts. 

Laboratories typically analyze multiple parameters in the urine, including creatinine levels, specific gravity, and pH, to assess the sample's validity. Diluted urine often has low creatinine levels and a lower specific gravity compared to normal urine, indicating that it has been tampered with.

laboratories routinely analyze samples for creatinine and specific gravity levels. Creatinine is a waste product generated by muscles and serves as a measure of urine concentration. Specific gravity, on the other hand, measures the ratio of water to other substances in urine and is another indicator of concentration. Typical creatinine levels in urine range between 20 and 400 mg/dL, while normal specific gravity falls between 1.002 and 1.030. Specimens with a creatinine level above 2 mg/dL or below 20 g/dL, and a specific gravity lower than 1.001 or 1.003, are considered diluted.

If a test is determined to be a negative-dilute result, it is highly likely that an employer will request a second test regardless of the underlying reason. However, in some cases, employers may accept a doctor's note stating that an individual has a shy bladder, which requires consuming large amounts of water to produce a urine specimen, as a valid explanation for a dilute test.

The outcomes of a positive dilute test are considered equivalent to any other positive test. The presence of drugs is detected, and the consequences remain the same.

 In drug testing scenarios, dilution is generally considered an adulteration method and is not a reliable way to pass a drug test. Laboratories are aware of these techniques and have established protocols to detect diluted samples. A negative dilute result occurs when a urine specimen tests Negative  for a particular drug metabolite while also having a crashed specific gravity and creatinine level.

 If a diluted sample is identified, it may be deemed invalid, and further testing or consequences may be implemented, such as retesting or considering it a positive result.

 

Methods of Dilution

 Various items are inevitably added to a standard dilution of consuming a liter a hour of some sports drink and diuretics. most notably would be creatine, certo or pectin , and some times you hear people saying to use charcoal. People cant help but think they are improving things regardless if they have any proof to the claim .

adding random things are pointless for one , your still diluting with tons of fluids.

If items like pectin were so important then why don't they drink it with a cup of water instead of a gallon ?  well besides that fact it would turn to a glob in their stomach .  Pectin is just fruit fiber and it may help you create a bowel movement its not releasing THC from body fat. Same goes for charcoal, which is consumed by mouth into the stomach where it is usually used to aid in poisoning JUST CONSUMED AND STILL IN THE STOMACH.  


consuming creatine will not give you extra creatinine levels

How Creatine Works

 Creatine is a substance found naturally in muscle cells. It helps your muscles produce energy during heavy lifting or high intensity exercise.

 Taking creatine as a supplement is very popular among athletes and bodybuilders. They use it to gain muscle, enhance strength, and improve exercise performance

About half of your body’s creatine stores come from the food you eat — especially red meat and seafood — and the rest is made in your liver and kidneys from amino acids. About 95% of the body’s creatine is stored in the muscles, mainly in the form of phosphocreatine. The other 5% is found in the brain and testes .

Creatine monohydrate absorption is close to 100% [27], and when 2 g of Cr is consumed in an aqueous solution, it reaches peak plasma concentration in approximately 1 h. 

 
During exertion, your muscles convert the stored creatine molecules into energy, which assists in muscle contraction. After being used for energy, creatine is broken down into creatinine, which re-enters the bloodstream en route to the kidneys. 

 
 When you supplement, you increase your stores of phosphocreatine. This is a form of stored energy in the cells. It helps your body produce more of a high energy molecule called ATP.

Most of the creatine in the body is stored as phosphocreatine (66%), while the remaining portion exists as free creatine (33%). On average, the total creatine pool (phosphocreatine + free creatine) in the muscles of a normal-sized person is around 120 grams. Each day, about 1 to 2% (2-3 grams) of the total creatine pool is broken down and converted into creatinine within the muscles. The creatinine is then excreted in the urine.

The body has the capacity to store up to 160 grams of creatine. Therefore, one can think of the normal creatine content in the muscles (approximately 120 grams) as a gas tank that is about 75% full. Scientific studies consistently report that dietary supplementation of creatine can increase muscle creatine and phosphocreatine content by 10-40%. Consequently, supplementing with creatine allows individuals to fill up their creatine storage tank to about 150-160 grams (25-30%). However, people may respond differently to creatine supplementation, with some experiencing increases in muscle creatine content as little as 5-15%, while others may see an increase of 15-40%.

TYPES OF CREATINE 

Creatine monohydrate and creatine ester are two forms of creatine, a popular supplement known for its potential to enhance athletic performance. Let's delve into the differences in absorption and their potential impact on creatinine levels: 

1. Creatine Monohydrate: 

• Absorption: Creatine monohydrate is well-researched and has been shown to be efficiently absorbed by the body. It is the most studied and commonly used form of creatine. 

• Creatinine Levels: Creatinine is a byproduct of creatine metabolism. While creatine monohydrate supplementation may lead to a slight increase in creatinine levels, this is generally considered normal and not indicative of kidney dysfunction. It's crucial to stay hydrated when using creatine to support kidney function. 

2. Creatine Ester: 

• Absorption: Creatine ester is a form of creatine that has been chemically altered to potentially improve absorption. However, research on creatine ester is limited compared to creatine monohydrate, and some studies suggest that the ester form may not be as effective in increasing muscle creatine levels. 

 it has been found that under normal physiological conditions, creatine ethyl ester is very unstable and is largely converted into creatinine in the gastrointestinal tract, where it is also absorbed. Spillane et al¹³ demonstrate this in an experiment in which serum creatine and creatinine measurements were taken from healthy volunteers who either consumed creatine ethyl ester, creatine monohydrate or a placebo. It was found that serum creatinine levels approximately tripled after the ingestion of creatine ethyl ester, while serum creatine only marginally increased. The ingestion of creatine monohydrate caused serum creatine to increase significantly and only caused a marginal increase in serum creatinine.

Therefore, regardless of the small amount consumed during a dilution method, it does not convert into creatinine but rather gets stored. Additionally, the amount of creatinine in so-called detox drinks like Q Carbo is extremely insignificant. Your body only excretes what it breaks down, which means you need to regularly consume creatine and engage in heavy weight lifting to create the waste material that is creatinine.

 HOWEVER  HERE IS THE GOOD NEWS 

There IS a way you can get  creatinine  not creatine in volume you need during dilution. You will need to prepare it ahead of time. 20 grams of creatinine mono hydrate in orange juice, (this is needed for the acid ) and store at room temp for 3 days. Now you have creatinine that can be rejected and pissed out .  

The effect of creatine ingestion on urinary creatinine concentration: Does supplementation mask a heavy dilution?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170516/

https://pubmed.ncbi.nlm.nih.gov/34559477/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401986/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649889/

What does true THC detox mean ?

                YOU CAN NOT DETOX THC WITH PRODUCTS  OR WATER 

 

 

Typically all DETOX questions revolve around removing THC for Urine drug test . All other drug will naturally be gone in 5 days average with some things a little longer  nicotine 10 + days , certain Benzodiazepines can be 3 + weeks.  however repeat use of THC can be much longer based on intake and weight / activity level .

THC, the active compound found in cannabis, is known to be stored in fat cells in the body. When someone consumes cannabis, THC is absorbed into the bloodstream and eventually gets distributed throughout the body, including the fatty tissues. Over time, the THC is gradually released from the fat cells back into the bloodstream, allowing it to be metabolized and eliminated from the body.

Sweating, on the other hand, does not significantly contribute to the removal of THC from the body. While small traces of THC and its metabolites may be excreted in sweat, the concentration is usually quite low and not considered a reliable method for eliminating THC from the body. The primary routes of THC elimination are through urine and feces.

in addition to cardio,  studies have found fasting to be effective at reducing and thus releasing fat and in turn THC stores . 

Lipolysis is the metabolic pathway through which lipid triglycerides are hydrolyzed into a glycerol and free fatty acids. It is used to mobilize stored energy during fasting or exercise, and usually occurs in fat adipocytes. The most important regulatory hormone in lipolysis is insulin; lipolysis can only occur when insulin action falls to low levels, as occurs during fasting.

Imagine your body as a little factory that turns food into energy. When you eat food, your body uses it for energy right away. But sometimes, when you're not eating, like when you're sleeping or taking a break from food, your body needs to find another way to get the energy it needs. That's where fasting comes in.

Fasting is like giving your body a little challenge. When you don't eat for a while, your body doesn't have any new food to use for energy. So, it starts looking for another source of energy, and that's when something special happens.

Your body has a special kind of fat called stored fat. It's like a backup energy supply. When you fast, your body starts to use this stored fat for energy. It breaks down the stored fat into smaller parts called fatty acids. This process is called lipolysis.

Think of lipolysis as a superhero that helps your body burn fat. It takes the big pieces of stored fat and turns them into smaller pieces that your body can use as fuel. These smaller pieces are the fatty acids.

So, when you fast, your body switches to using the stored fat and breaks it down into fatty acids through lipolysis. This helps your body burn fat and gives you the energy you need to keep going, even when you're not eating.

Remember, fasting is like a challenge for your body, and it helps your body use stored fat through lipolysis to get the energy it needs.

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NOW WHAT ABOUT HYDRATION AND  DETOX PRODUCTS

 The concept of "detoxing" is often associated with various health practices and products, including detox teas. However, it's important to understand that the idea of detoxification and flushing out toxins is not scientifically well-supported.


The human body has its built-in detoxification systems, primarily the liver and kidneys, which work continuously to eliminate waste products and toxins from the body. They are highly efficient at their job and do not require any additional assistance from detox teas or similar products.


While some detox teas may contain ingredients that can have diuretic or laxative effects, leading to increased urination or bowel movements, these effects do not necessarily equate to flushing out toxins. Moreover, excessive use of such teas can disrupt the body's natural balance and lead to dehydration or electrolyte imbalances.


It's worth noting that the term "detox" has been marketed and used in a variety of ways, often with exaggerated claims and unsupported scientific evidence. If you're concerned about your health or believe you may have been exposed to harmful substances, it's best to consult with a healthcare professional who can provide appropriate guidance based on your specific situation.

 

SO THATS THAT   IF YOU WANT TO DETOX THC AND HAVE THE TIME   

IF NOT  THEN USE Fake It  SYNTHETIC URINE

 

 

 

 

 

What are the risk with "Dilution" for Passing Urine Drug Test

What is a Dilution  method for urine drug test?

A urine drug test is a common way for employees, healthcare providers, and law enforcement agencies to detect the presence of drugs in an individuals system. One method used to try and pass a urine drug test is through dilution.  In regards to drug test, " Dilution " means  - the method to pass a urine drug screen by ingesting  large amounts of liquids to Dilute your bladder and thus dilute your metabolite levels below the cut off point. 

 

How Dilution methods work  

  The liquid need only be water but best if it is also a diuretic. Diuretics help the body get rid of excess fluid, mainly water and sodium.When diuretics stimulate kidneys to flush away sodium the body also flushes away water. This can be done by using herbal items such as dandelion root, horsetail, celery seed, green or black teas or coffee.

 By drinking large amounts of fluids, individuals aim to lower the concentration of drug metabolites in their urine sample, making it more difficult to detect. 

 What makes Dilution Risky ? 

The truth about dilution for drug testing is that it does not detoxify the body but only dilutes the urine with water. Substances like certo,  ( which require large amounts of  WATER)  and expensive detox drinks do not "detoxify" the body either are they diuretics. After consuming these the body's urine is diluted with water for a relatively short window. This creates a clear urine sample which is actually not unnatural as most drink extra prior to test but  promoters of the dilution method will say to just take B vitamins for color and creatine supplements.  However your still diluting it and if does add any color it will be a suspicious fake neon yellow.  Also Color is not a qualifying parameter so why mess with it ?  As for creatine supplements - this is another sweet spot factor in timing of consumption to get it the creatine to convert to creatinine as shown in study  "  The effects of creatine ingestion on urinary creatine concentration: Does supplementation mask heavy dilution? ". Proper use of creatine for the  purpose of suplementing during dilution requires 20 grams to be hydrated in acid or orange juice for 3 days then consumed prior to testing  so that all the cratine is converted to creatinine . " Detox" rinks like q carbo are mostly herbal tea and contain VERY little insignificant amount of creatine considering your still DILUTING IT. 

 

The Trick is that you have to ingest enough fluids to dilute your urine and metabolite levels to below threshold but NOT to point that your creatinine and Specific gravity (urine density), which is what results in a DILUTED result. Dilution results are also effected by sex and weight as seen in this study "Creatinine excretion in consecutive urine samples after controlled ingestion of water" .  Dilution is not permanent, as you urinate you remove water and body returns to previous levels. You have to hit the sweet spot during a short window, without coming up diluted.  

Urine drug screens are performed by measuring amounts of drug metabolites and if they fall over a threshold your deemed POSITIVE and if under your negative.  However Lab drug tests have two parts, including the Specimen validity testing (SVT). SVT is done to check for substitution or a sample that is not characteristic of human urine.

 The Validation screen which is performed prior to or simultaneously with drug screen. Specimen validity testing (SVT) is performed on a urine drug screen specimen to detect substances, adulteration, or dilution ( result from creatinine and specific gravity levels being crashed or under limits).

  The validation screen will also look at non human items such as sanitizing agents used in liquid urine or masking agents (adulteration). Adulteration involves adding chemicals to destroy the drug metabolite. 

 WHEN SELF TESTING  THEY DO NOT LOOK AT SPECIFIC GRAVITY AND COULD GIVE A FALSE NEGATIVE   YOU WANT TO TEST SG TO VERIFY IF OUR TOO DILUTED SO YOU KNOW YOUR WINDOW BASED ON FLUID INTAKE OVER TIME

 Alternatives to Dilution methods.

 Detoxing 

 

All drugs will be gone from urine in 3-5 days except repeated use of THC as it builds up and stores in body fat and liver.  However if you are a repeat user of THC and if your non active heavy body mass person you may not have the 1-2 month needed.

 

Adulteration 

Not even going to bother as this is a major part of the SVT 

 

 

Synthetic Urine Substitution  

This is the most effective method for passing a urine drug test every single time providing your not on observed probation  or (depending on the labs validation screen parameters ) a liquid urine as they all contain a sanitizing agent to keep them shelf stable.  Powdered synthetic urine avoid this risk but requires pre mixing which is not a major issue. I have personally done 2 pre employment and 5 randoms using synthetic and i can say once you do it and get over the jitters you feel bullet proof from then on.

 

 

"But im too scared ill get caught " 

 

 The only concern with synthetic is getting the urine in the cup at temperature.  

Simply practice carrying with water and warming pads to get rid of being nervous.

To conclude

  basically dilution is a 50 50 crap shoot with success based on your use level, amount of liquid consumed and timing it before level return to measurable levels so as to not OVER DILUTE. IF your going to attempt it I suggest you practice by doing said method and  using  a self pre test with some cheap test sticks.